Prof. Dr. med. Philipp Steven

Prof. Dr. med. Philipp Steven

Department of Ophthalmology
Ocular Surface Group
Competence Center for Ocular GvHD
University of Cologne
50937 Cologne, Germany
Tel. (+49)-221-478 97790
Fax. (+49)-221-478 97536
Email: philipp.steven@uk-koeln.de

Projects:

Project leader

B01

Scientific career

1996-2003 Study of Medicine at the Christian-Albrechts-University of Kiel

2000, 2003 Research sabbaticals at the Institute of Anatomy and Centenary Institute, University of Sydney, Australia

2003 M.D. (magna cum laude) at the Christian-Albrechts-University of Kiel

2004-2006 Resident of Ophthalmology and Head of the Laboratory for Experimental Ophthalmology, Eye Hospital, University of Lübeck

2006-2008 Postdoctoral fellow at Institute of Anatomy, University of Lübeck (Laboratory of Prof. Dr. Andreas Gebert)

2007- Principal Investigator, Ocular Surface Group

2009 Board Certificate (Facharzt) for Ophthalmology

2011 Habilitation and Venia Legendi at the Faculty of Medicine, University of Lübeck

2011- Clinician-Scientist at the Department of Ophthalmology, University of Cologne

2013-2015 Board Member, Section Young Ophthalmologists, German Ophthalmological Society

2014- Principal Investigator, Cluster of Excellence CECAD, University of Cologne

2014 Habilitation and Venia Legendi at the Faculty of Medicine, University of Cologne

2014- Speaker and Director Competence Center for Ocular GvHD

2015- Principal Investigator of Central Project 1  “Cologne Experimental Eye Imaging Center (CEE-IC)” of the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne

2016- Scientist in the Horizons 2020 research consortium ARREST BLINDNESS, funded by the European Union, an associated project of the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne

2018- Principal Investigator of Project N1 “Lymph- and hemangiogenesis in ocular Graft-versus-Host Disease” of the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne

2018- Co-Applicant of of Central Project C1  “Cologne Experimental Eye Imaging Center (CEE-IC)” of the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne

Prizes and honors

2002 Dry Eye Research Prize, German Ophthalmological Society, Berlin

2007 Dry Eye Research Prize, German Ophthalmological Society, Berlin

2008 Dry Eye Research Prize, German Ophthalmological Society, Berlin

2008 Heinrich Dräger Research Prize

2009 Dry Eye Research Prize, German Ophthalmological Society, Berlin

2016 Clinical Applications part of the two-part Science Prize for Dry Eye and Blepharitis/Meibom-Gland-Dysfunction (MGD), German Ophthalmological Society, Berlin

Selected publications

  1. Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P. Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease. Transplant Cell Ther. 2022 Nov;28(11):782.e1-782.e7.
  2. Setu MAK, Schmidt S, Musial G, Stern ME, Steven P. Segmentation and Evaluation of Corneal Nerves and Dendritic Cells From In Vivo Confocal Microscopy Images Using Deep Learning. Transl Vis Sci Technol. 2022 Jun 1;11(6):24.
  3. Tran BN, Maass M, Musial G, Stern ME, Gehlsen U, Steven P. Topical application of cannabinoid-ligands ameliorates experimental dry-eye disease. Ocul Surf. 2022 Jan;23:131-139.
  4. Gehlsen U, Stary D, Maass M, Riesner K, Musial G, Stern ME, Penack O, Steven P. Ocular Graft-versus-Host Disease in a Chemotherapy-Based Minor-Mismatch Mouse Model Features Corneal (Lymph-) Angiogenesis. Int J Mol Sci. 2021 Jun 8;22(12).pii: 6191.
  5. Setu MAK, Horstmann J, Schmidt S, Stern ME, Steven P. Deep learning-based automatic meibomian gland segmentation and morphology assessment in infrared meibography. Sci Rep. 2021 Apr 7;11(1):7649.
  6. Steven P, Faust C, Holtick U, Scheid C, Tahmaz V, Stern ME, Gehlsen U. Adverse environmental conditions are a risk factor for ocular GvHD after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2020 Sep;55(9):1851-1853.
  7. Steven P, Augustin AJ, Geerling G, Kaercher T, Kretz F, Kunert K, Menzel-Severing J, Schrage N, Schrems W, Krösser S, Beckert M, Messmer EM. Semifluorinated Alkane Eye Drops for Treatment of Dry Eye Disease Due to Meibomian Gland Disease. J Ocul Pharmacol Ther. 2017 Nov;33(9):678-685.
  8. Gehlsen U, Braun T, Notara M, Krösser S, Steven P. A semifluorinated alkane (F4H5) as novel carrier for cyclosporine A: a promising therapeutic and prophylactic option for topical treatment of dry eye. Graefes Arch Clin Exp Ophthalmol. 2017 Apr;255(4):767-775.
  9. Steven P, Bock F, Hüttmann G, Cursiefen C. Intravital two-photon microscopy of immune cell dynamics in corneal lymphatic vessels. PLoS One. 2011;6(10):e26253.
  10. Steven P, Rupp J, Hüttmann G, Koop N, Lensing C, Laqua H, Gebert A. Experimental induction and three-dimensional two-photon imaging of conjunctiva-associated lymphoid tissue. Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1512-7.